Sentence examples for several developmental defects from inspiring English sources

At the end of gastrulation, the Dlg3 mutant mouse embryos present with several developmental defects of variable severity, such as an absence of embryonic turning, posterior truncation and forebrain deletion.

The quaking viable (qkv) mouse has several developmental defects that result in rapid tremors in the hind limbs.

The reduced expression of PARP3 leads to several developmental defects caused by inappropriate ectodermal and neural crest cell differentiation, indicating that it is essential for vertebrate development.

Plants lacking AtMTR4 are viable but have several developmental defects, including aberrant vein patterning and pointed first leaves [ 75].

AGO1 is the main protein mediating miRNA post-transcriptional directed regulation and ago1 mutants show several developmental defects [ 28].

We have previously shown that a mutant allele of the homeodomain transcription factor Prospero (prosVoila1, V1), presents several developmental defects including abnormal growth and altered taste responses.

In accordance with this increased expression during embryogenesis, depletion of XPR72 in Xenopus embryos caused several severe developmental defects (defects in somite formation, a short axis phenotype and lack of eye differentiation) [ 15].

Indeed several reports have shown severe developmental defects in Arabidopsis in response to inappropriate [Fe-S] biogenesis such as embryo lethality in both AtSufE and AtSufC loss-of-function mutants [26], [27].

The loss of several HD-ZIPIII genes, as in the case of the phb phv rev triple mutant, causes severe developmental defects, including consumption of the apical stem cells (Emery et al., 2003; Prigge et al., 2005).

In mice, disruption of Lrp6 causes severe developmental defects [13].

Modification of MIRNA gene expression leads to severe developmental defects.