The generated convoluted spectra were used to evaluate the capability of several database search methods – SEQUEST, Mascot, X!Tandem, OMSSA, and RAId_DbS – in identifying true peptides from superimposed spectra of co-eluted peptides.
Once a surrogate peptide binder has been identified and shown to bind specifically to its target, it is subjected to partner analysis using several different database search programs.
Despite searching several databases, using broad searches, scanning nearly 6,000 titles, and reviewing papers in several languages, our requirement that included epidemics involve post-World War II western populations limited us to identifying only 45 separate outbreaks, some of which were divided for analysis.
The decision in this act to allow large-scale data matching exercises - a fishing expedition in which several databases are searched to identify suspicious patterns of activity – marks a major shift in the government's rules on data sharing.
Several databases were searched, including MEDLINE, EMBASE, LILACS, and CENTRAL.
Several databases were searched to identify relevant literature.
Several databases were searched including PubMed, CINAHL, Business Source Premier, Web of Science, and Scopus.
Each ranking category reflects the strength of evidence that a variant may adversely affect gene function from several standpoints, incorporating both database searches and sequence-based predictions.
Like all database searches, several possible matches for each query were returned, and the final step in our analysis was manual inspection of BMRB spectra overlaid onto our primary data and covariance maps for final identification.
