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Several compounds with low nanomolar inhibitory potency are reported.
Several compounds with biological activity on TLR2 signaling in general and TLR1 signaling specifically were identified.
Subsequent structure-activity relationship (SAR) studies identified several compounds with mixed antibacterial and antitubercular profiles.
Laccases have low substrate specificity; this characteristic allows the degradation of several compounds with a phenolic structure [17].
Several compounds with single-digit or even sub-nanomolar potency, suitable for further elaboration of the nitrile moiety, were identified.
The authors used a combination of ligand-based screening and structure-based molecular docking to identify several compounds, with acyclovir predicted as most active, for experimental assays [42].
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A detailed metabolic profiling of different tissues (flavedo, albedo, seeds, and pulp) of both lemon and citrus fruits was conducted through HRMAS as well as they characterized several compounds associated with the development of mold in the citron flavedo [57].
Several compounds cooperate with RA in inducing NIS expression in BC cell lines.
They transport several compounds associated with multidrug (antibiotic) resistance which can inhibit pathogen infection in animal model [ 41, 43].
In addition, several compounds interfering with NS1/viral RNA binding were identified either through virtual or high-throughput screening methods 113, 114.
In addition, several compounds interfering with bioactivation pathways proposed previously, in particular cytochrome P450 and GSH-transferase, had no considerable effects or were unsuitable for various reasons.
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