Sentence examples for several common variants from inspiring English sources

Therefore, a disorder dominated by a polygenic model will be one in which several common variants of modest effect contribute to risk for disease in each affected individual.

Moreover, several common variants near hypothalamic genes such as MC4R and POMC have been identified associated with body mass index (BMI) in a recent genome-wide association study [7].

The success of this approach relies on the common disease-common variant (CDCV) hypothesis, which presumes that phenotypic variation of common diseases is explained by several common variants, each with a relatively small effect [1], [2], [3].

Although several common variants as well as the kringle(IV) repeat have previously been shown to contribute to African-European differences [10], these earlier studies were performed without estimates of LPA local ancestry.

Additionally, several common variants in genes located in linked regions were assessed for association with AD.

Several common variants in the IL-23 receptor gene (IL23R) are reported to be clearly associated with both CD and UC susceptibility [ 10].

Several common LPL variants were reported to modulate lipid levels and CVD risk.

Several common gene variants are more strongly associated with specific cancer subtypes.

Large genome-wide association studies have identified several common genetic variants associated with complex diseases.

Several common genetic variants increasing the risk of OAG have recently been identified through genome-wide association studies (GWAS; Table 1).

Many genome-wide association studies (GWASs) have been conducted assuming that long-lived individuals could share several common genetic variants that influence human lifespan.