Sentence examples for several checkpoint from inspiring English sources

The secondary signal is provided through one of several checkpoint receptors (Table 10), which can either provide a costimulatory signal to activate the T cells, or a blocking signal to dampen T cell response (Topalian et al., 2015).

Several "checkpoint inhibitor" drugs, which release the immune system's natural brakes so that it can attack cancers, have been approved by the Food and Drug Administration and are showing early successes in treating melanoma and cancers of the lungs and kidneys.

Mps1 exerts this control, at least in part, through regulating kinetochore localization of several checkpoint proteins including Mad1 and Mad2 [11] [12], [12].

We found that expression of Rpn4*, while imposing no effect on DNA checkpoint activation, displays a synthetic growth defect with deletion of the MEC1 checkpoint gene and sensitizes several checkpoint mutants to DNA damage.

Using yeast genetics and biochemical approach we show that inhibition of Rpn4 degradation displays a synthetic growth defect with deletion of the MEC1 checkpoint gene and sensitizes several checkpoint mutants to DNA damage.

Several checkpoint proteins bind close to DSBs.

Photographs from several checkpoints.

Several checkpoints for cars remain.

We pass several checkpoints without trouble.

The kidnappers breezed through several checkpoints.

Security at the hospital's entrance was tight, with Iraqi police officers at several checkpoints.