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The spectrin membrane skeleton is a ubiquitous cytoskeletal structure with several cellular roles, including the maintenance of cell integrity, determination of cell shape and as a contributor to cell polarity.
Based on the phenotypes resulting from its knockout, several cellular roles for the translocon β subunit have been proposed.
Heterogeneous ribonucleoprotein K has several cellular roles including transcription, mRNA splicing and translation.
The dysregulation of hnRNP K cellular localisation in colon cancer is suggestive that the protein has an altered cellular function, which is not surprising, as the protein has several cellular roles including, transcription, translation, mRNA shuttling and RNA editing.
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The tumor suppressor menin (MEN1) is mutated in the inherited disease multiple endocrine neoplasia type I, and has several documented cellular roles, including the activation and repression of transcription effected by several transcription factors.
Several predicted cellular roles were also enriched (Table 4).
Heterogeneous ribonucleoprotein K (hnRNP K) is a member of the hnRNP family which has several different cellular roles including transcription, mRNA shuttling, RNA editing and translation.
HA is a non-immunogenic, non-adhesive glycosaminoglycan that plays significant roles in several cellular processes, including angiogenesis and the regulation of inflammation.
The HOG (High Osmolarity Glycerol response) pathway plays central roles in several cellular functions in filamentous and non-filamentous fungi, encompassing both pathogens and non-pathogens.
Additionally, the Y-family DNA polymerases may play critical roles in several cellular processes beyond TLS.
Thus it can serve as a scaffolding protein and have roles in several cellular processes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com