Sentence examples for several cellular models from inspiring English sources

Phthalocyanines (Pcs) are good photosensitizers (PSs) for PDT because they induce cell death in several cellular models.

For the carcinoma cell compartment of the co-culture, we selected several cellular models where mutp53 was either expressed (the R248W mutant in HCT116 cells), induced (the V157F, R175H, R273H or R249S in H358 cells), or knocked-down (the R273H in HT29 cells) (Supplementary Fig. 1c).

We and others have shown that DYRK1A is important for phosphorylation of tau protein on multiple sites in several cellular models [3], [4], [6], [7].

Studies performed in several cellular models have shown that availability of dNTPs and therefore the regulation of their synthesis, plays a critical role in DNA replication [49].

It has been shown in several cellular models that the exposition to high concentrations of saturated and unsaturated FA promotes TG synthesis and prevents lipotoxicity by sequestering FFA that are otherwise cytotoxic [44].

Its role in cell death has previously been reported in several cellular models including neuroblastoma.

This linkage has been demonstrated in several cellular model systems [ 27, 28], in particular in plants [ 29- 31], using cellular models characterised by high cell proliferation activity.

Several groups have studied DPR protein toxicity in various cellular models but these have generated conflicting results [ 15– 17, 20, 21].

The activation of the p38 MAPK pathway is required for apoptosis induction in several different cellular models [20] [23].

JNK activity has also been linked to adverse metabolic outcomes in several critical cellular models and tissues.

Our recent report, where in which we have used several experimental cellular model systems to define direct caspase activation, demonstrated that PAC-1 essentially requires cytochrome c (cyt. c) release from the mitochondria and Apaf-1 to induce caspase activation.