Although the authors of that study used a different functional classification, several cellular functions regulated by ArcA according to that analysis were also identified in our experiments (Table 2), such as amino acid biosynthesis and metabolism, carbon compound catabolism and energy metabolism.
Two-component systems (TCSs) are signal transduction mechanisms present in many eukaryotes, including fungi that play essential roles in the regulation of several cellular functions and responses.
Using a highly metastatic murine lung carcinoma model, it was demonstrated that this receptor regulates several cellular functions that can impact on the metastatic potential of the cells, including cellular proliferation, anchorage-independent growth, cell migration, and invasion.
Aberrant cell proliferation requires deregulation of several cellular functions or pathways, including cell cycle progression.
Mitochondria are key players in several cellular functions including growth, division, energy metabolism, and apoptosis [22].
Our study was performed using primary human monocytes in which productive EBV infection and viral-mediated alteration of several cellular functions have been demonstrated [3].
In addition to its role in Phox activation, Rac acts as a molecular switch for signal transduction to regulate several cellular functions.
Through associations with many additional proteins, PML-NBs control several cellular functions including p53 activation, apoptosis, senescence, DNA damage repair and innate antiviral responses [4].
This domain is known to be involved in several cellular functions, such as signal transduction, cell-cycle control and apoptosis [24].
TPR-containing proteins are involved in several cellular functions such as molecular chaperone complexes, anaphase promoting complexes, transcription repression complexes, protein import complexes and protein folding [7].
Molecular diversity within envelope (env) sequences of retroviruses and other viruses influence several cellular functions including susceptibility to infection, immune responses, growth and survival [12].
