Sentence examples for several cellular effects from inspiring English sources

Hyperthermia itself has several cellular effects that should be synergistic with radiation-induced tumor cell death.

Activation of the PI3K pathway leads to several cellular effects including cell growth, survival, chemotaxis and actin reorganization [15], [22].

Conversely, recent in vivo studies suggested that the inhibition of the mevalonate pathway by N-BPs lies downstream the FPP synthesis step; indeed, several cellular effects of N-BPs such as inhibition of osteoclast formation[ 10], inhibition of ovarian cancer cell migration [ 11] or inhibition of breast cancer cell invasion [ 12] were reversed only by GGOH but not by FOH.

In astrocytes, ATP stimulates Akt phosphorylation, where calcium, PI3K and a Src family kinase are involved (Jacques-Silva et al., 2004), which may result in several cellular downstream effects related to the Akt pathway, such as glycogen synthesis (Brazil and Hemmings, 2001).

The mechanisms by which trastuzumab induces regression of HER2-overexpressing tumors are still being elucidated, but several molecular and cellular effects have been reported in the literature [ 8].

Several molecular and cellular effects have been observed, including inhibition of HER2 extracellular proteolysis, disruption of downstream cellular pathways, cell-cycle arrest, inhibition of DNA repair, suppression of angiogenesis, and induction of antibody-dependent cell-mediated cytotoxicity.

Several studies suggest that cellular effects of VDR may be associated with MAPK signaling pathways, especially KRAS mutation in several cancer types such as breast and colorectal cancers [ 48, 49].

In addition to expected indicators of AH exposure, the RNA-Seq based techniques used here revealed effects on several cellular systems, such as the immune response and effects on the wide variety of ribosomal proteins, that might not have been specifically interrogated by a more focused examination of specific pathways through smaller-scale techniques.

To evaluate the chemical reactivity and cellular effects of several of these oxidation products, we synthesized a series of electrophiles related to HNE and its oxidation product, ONE (Scheme 1).

Curcumin is a natural product from Curcuma longa with multiple bioactivities and is known to have cardioprotective effects in several cellular and animal models.

Direct regulation of a subset of cellular promoters containing putative EBNA-1 binding sites and direct or indirect effects on several cellular transcription factors may initiate a transcription cascade that is greatly amplified upon prolonged EBNA-1 expression.