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Reactive oxygen species (ROS), mainly formed in mitochondria, can impair the function of several cellular components and produce cell oxidative stress by changing the normal red-ox status of the major cell antioxidants as glutathione.
In this regard, tellurite toxicity was initially thought to arise mainly from its ability to oxidize several cellular components [5], [6], [33].
The tight regulation of cytosolic Ca2+ concentration requires the activity of several cellular components.
Our results identified several cellular components, including genetically intact mitochondria, as critical to maintaining wild-type extracellular ATP levels.
Anticancer drugs target several cellular components and activate responses that go from cell repair to cell death [ 16, 17].
Several cellular components have been suggested to comprise the endosteal niches; these include osteoblasts, CXCL12 abundant reticular cells (CAR), osteoclasts and sympathetic neurons [ 13, 16- 18].
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In the first one, RecA interacts with one or several cellular component(s) expressed (or activated) during the swarming differentiation process, but not during swimming motility.
GO categories enriched significantly in the low ATP group included mitochondrial translation, tRNA aminoacylation, ATP Synthesis, and several cellular component categories associated with the mitochondria (Table 1).
For molecular functions, several cellular-component GO terms were identified, especially those associated with the plasma membrane representing the largest group.
Splicing is carried out by the host cell splicing machinery, but is likely regulated by NS1 [ 89, 90], which binds to several cellular splicing components such as U6 small nuclear RNAs [ 91, 92] and UAP56, a splicing factor involved in spliceosome formation [ 93, 94].
In the cellular component category, several key cellular components were identified, such as cell part, membrane and ribosome.
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