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Since that time, numerous miRNAs have been found to interact either directly or indirectly with EMT machinery in several cell models [43].
Furthermore, P3A1-MWCNTs are cytotoxic to several cell models of breast cancer and induce S-phase cell cycle arrest and non-apoptotic cell death in breast cancer cells.
We initially induced HK II detachment from the OMM with clotrimazole, a drug that efficiently dissociates HK from mitochondria in several cell models [e.g. 4], [14], [17].
In fact, in previous works carried out in several cell models it was also reported that over-activation of RNase L stimulated apoptosis [34], [35].
DPE or UVA has been reported to exhibit significant genotoxicity and cytotoxicity in several cell models.
The endocrine-disruptive effect of atrazine on CYP19 has been studied in several cell models (Fan et al. 2007; Sanderson et al. 2000).
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Within the past few years, several cell culture models as well as single, double and, more recently, triple transgenic mouse models have been developed that reproduce diverse aspects of AD.
Regeneration/sprouting of the 5-HT fiber tract has been previously shown in several cell transplantation models via grafting of BDNF and NT-3 producing fibroblasts into injured rat spinal cords [11], [14], [41], [44], [45].
Similarly, the cAMP signaling cascade can promote astrocytic commitment in several cell culture models, such as the C6 glioma cell line.
Low caspase 8 levels were previously shown to contribute to rhTRAIL resistance in several cell line models and tumours (Hopkins-Donaldson et al, 2000; Zhang et al, 2005).
Expression of expanded polyglutamine tracts catalytically inactivates GAPDH (iGAPDH), which triggers its selective association with damaged mitochondria in several cell culture models of HD.
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