Sentence examples for several alternative splicing from inspiring English sources
The results of the present study indicate that the sequence composition of introns at the vicinity of alternate exons is indeed different whether only one or several alternative splicing decisions are engaged.
Siglec G and its human orthologue Siglec 10 appears to have several alternative splicing variants [17], [18] [15], [15].
The 75.44 Kb sls gene consists of 37 exons and several alternative splicing have been described [ 78].
Owing to the presence of several alternative splicing sites and multiple phosphorylation sites, tau protein usually appears on immunoblots as multiple bands of approx. 52 68 kDa.
It has been reported that spliceostatin A, another splicing inhibitor that binds SF3b, strongly inhibited splicing of MDM2 and produced several alternative splicing variants in a rhabdomyosarcoma cell line.
In these models, SRSF1 overexpression promoted cell proliferation and antiapoptotic pathways, mainly reflecting the combined effects of several alternative splicing variants which were activated by the concentration-dependent changes in SRSF1 availability.
Recent research has identified several alternative splice variants of Rela, e.g. p65A, p65A2 and p65A3.
In addition to the known mef2ca transcript [32,42], we detected two alternative 5′UTR sequences and several alternative splices (Fig. 1A and B).
Indeed, a candidate Prl2c gene exists in this location in mice (ENSMUSG00000062551) and is currently predicted to have several alternative splice variants.
Several alternative splice transcripts of AID have been reported in activated B cells as well as malignant B cells such as chronic lymphocytic leukemia (CLL).
Furthermore, several alternative splice variants for the mammalian δ-tubulin genes can be identified in the cDNA/EST databases, although most are probably pseudoisoforms resulting in nonfunctional proteins (supplementary fig. S10, Supplementary Material online).
