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We monitored several active sites on the forelands of two glaciers, Ebbabreen and Ragnarbreen, both of which are located near Petuniabukta at the northern end of Billefjorden in Spitsbergen.
These molecules are a relatively complex conjugate system with several active sites.
"Snow flakes are ice particles with various types of surfaces, including several active sites, that can absorb various gaseous or particulate pollutants," she told The Huffington Post.
Fortunately, FN contains several active sites that serve as scaffoldings for cell anchorage [ 11], known as the heparin-binding domains, collagen-binding domain, fibrin-binding domain and cell-binding domain, respectively.
Several active sites on the α1 chain have been found to promote B16 F10 melanoma lung colonisation and here we have determined whether additional tumour promoting sites exist on the β1 and γ1 chains.
Noller [ 19] has proposed that the ribosome evolved from "smaller functional units capable of carrying out the different translational steps such as peptidyl transfer, decoding, and so on", similar to the view of Penny and co-workers, who have stated, "It is possible that the several active sites of modern ribosomes evolved as separate ribozymes" [ 4].
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It has been shown that new activity can be introduced by simultaneous incorporation and adjustment of functional elements through insertion, deletion, and substitution of several active site loops, followed by point mutations to fine-tune the activity [ 73].
Calorimetric analysis of several active site variants confirmed the roles of residues critical to the function of CpMnBP1.
The structure revealed several active site residues (Y12, N92 and R196) in CpMan5B that are not present in the active sites of other structurally resolved GH5 enzymes.
Activity assays of mutants of KRs from the first and second modules of the amphotericin PKS reveal the relative contributions of several active site residues toward catalysis and stereocontrol.
Site-directed mutagenesis and a comparative characterisation of the kinetic parameters, pH dependency of activity and thermal stability of mutant and wild-type enzymes have been used in association with crystallographic analysis to delineate the functions of several active site residues in a novel glycoside hydrolase family 8 xylanase.
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