The domains of Jacobson's theoretical framework, initially developed for high-income settings, are of relevance to the low- and middle-income country context, but may need modification to be fully applicable to these settings.
These results can help to improve quality of ethical practice in pediatric settings and are of relevance for teaching and policy makers.
Therefore, before cost-effectiveness results from one setting can be applied to inform decision making in other settings, the relevance of such context specific factors should be evaluated by considering the impact of the differences on the results and conclusions.
In all three integrated care settings the relevance of the elements was considered high.
This is a significant finding as in non-western post-conflict settings the relevance of diagnostic categories is questionable.
This implies that personal experiences did not differ greatly between settings, and results may be of relevance to wider populations of health researchers in resource-poor contexts.
However, our qualitative approach enabled an investigation of diversity in quality conceptualizations across different settings and groups which is of relevance for understanding QI processes, implementing improvement efforts, and bridging language and meaning about quality between system levels, professions, and clinical services [ 1, 5, 49, 55].
There are reports indicating a central role for MMPs in increasing permeability of the blood-brain barrier in inflammatory settings [ 52], which could be of relevance in SLE.
15 Nicaragua's history of community mobilization, however, raised issues of relevance to other settings.
However, in accordance with the notion of transferability, the findings of this study have highlighted issues that may be of relevance in other settings.
