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The low socio-economic status of marginalized, disadvantaged, and precarious populations in urban settings has been linked to adverse health outcomes including chronic and infectious disease, negative health behaviours, barriers to accessing health care services, and overall mortality.
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In resource-constrained settings maternal depression has been linked directly to higher rates of stunting, diarrhoeal diseases, infectious illness and hospital admission among infants, reduced completion of recommended schedules of immunization, and worse cognitive, motor, social, behavioural and emotional development in young children [ 4- 9].
In addition, three-quarters of the participants were from urban settings, a factor that has been linked to development of atopy [ 9].
8 9 Guidelines therefore continue to recommend prompt and rapid fluid administration for the treatment of paediatric shock in these settings, 10 as this has been linked with improved survival odds.
Assessments of the impact of teamwork have occurred in medical settings such as operating rooms [ 14] and emergency departments [ 15]; furthermore, teamwork has been linked to patient safety [ 16] in well-resourced settings.
The use of illegal pesticides such as aldicarb for rodent control has been linked to human poisonings in poor settings in South Africa, Brazil, Zimbabwe, the United States and Israel [ 2, 10- 17].
LKB1/AMPK regulation of mTOR has been linked to the regulation of autophagy in different settings, for example in autophagy stimulated by fluid flow over the primary cilium of epithelial cells20, and in cancer cells21.
The hypermethylated status of the promoter CpG island has been linked to gene transcription silencing in a number of biological settings.
Preoperative and postoperative hyperuricemia has been linked to a higher incidence of postoperative AKI, especially in cardiovascular surgery settings [ 8– 12].
Body awareness has been linked to female sexual response in laboratory manipulation studies and is used in clinical settings to ameliorate sexual difficulties.
Historically, Medicaid has been linked to demography.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com