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This would require mathematical optimization algorithms, e.g. in form of linear programming [120] which in turn makes it much more difficult to understand the relation between scenario settings and optimization results.
According to the poor hyperparameter setting detection rates (Tables 15, 16, 17, and 18), on average, approximately 8, 1, 33, and 26% of executions in each experiment are detected as having poor hyperparameter settings and optimization is accelerated in proportion to the detection rate.
Implementation of procedure-specific settings and optimization in artefact or technical alarm detection could improve patient surveillance and safety.
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For alignment, we used the default settings and the automatic optimization option in the online version of MAFFT95.
There is a workaround to fix the issue on the China device, and it requires digging into settings and turning battery optimization off.
Details about spectra acquisition, MS settings, SRM-assays generation and optimization can be found in Additional file 12: Supplementary Methods.
Isolate similarity dendrograms were generated for PFGE analysis using the BioNumerics version 5.10 software (Applied Maths, Belgium), by the unweighted pair group method with arithmetic mean (UPGMA) with tolerance and optimization settings of 1%, as previously described [ 21].
This benchmark was repeated for numerous sets of parameter settings and also used for parameter optimization (benchmark 2).
Although there were still some discrepancies in the reported values for each endpoint, the overall relationship between experimental groups was preserved, highlighting the need for continued validation and optimization of automated detection settings (see optimized settings in Fig. S2 of Supporting Information).
For a list of all the available methods and statistic settings, see the Sherpa Statistics and Optimization Methods pages.
Changing default values for optimization settings and convergence criteria should not be considered unless the impact of these changes is understood.
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