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But even its upbeat ending takes place in a setting of substantial "defeat".
Testing of AMA-1/AS02A in a pediatric Phase 2b, placebo-controlled trial in Bandiagara, Mali, an epidemiologic setting of substantial AMA-1 allelic diversity, is currently ongoing (www.clinicaltrials.gov NCT00460525).
In contrast, recipients of short-course CSA combined with host Th2.R cell therapy had minimal myocardial necrosis in the setting of substantial mononuclear cell infiltration; importantly, recipients of short-course CSA plus Th2 cells on day 0 of transplant had a statistically significant reduction in rejection by standard histology criteria (Fig. 5b).
One potential explanation for this finding may result from an inherent desire for confidentiality in this setting of substantial anti-abortion stigma.
The Fridericia method for correcting the QT interval for heart rate is often not fully adequate in the setting of substantial heart rate increases and commonly results in overcorrection and inflated QTcF increases, independent of repolarization 34.
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There's a big stretch role I've been eyeing for next year, which will involve a geographic relocation and a set of substantial changes for my social life, and I've been wondering if it's worth disrupting everything for such a big leap (and if I'm even qualified to vie for it in the first place).
Parsimonious: To be administratively meaningful, only a small set of substantial clusters should be identified.
The set of substantial and instrumental rules provides basic orientation for development as well as criteria to assess different states or development paths.
The basic idea of this last division seems to be that modes of being and natures of the accidental forms determine the set of substantial items which can play the role of their substrate.
Another set of substantial burdens pertains to the affliction-avoiding interventions one may have to engage in when a substantial genetic risk has been found (e.g. the strains of undergoing IVF/PGD cycles).
We used the 3-year data set because of substantial and unexplained reduction in reported mortality over the 3-year period, which could not plausibly be due only to differences in actual death rates.
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