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To further validate the robustness of our dating methodology, we performed a simulation using only tip dates, without setting a prior for the root height of the tree.
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Set a prior function prior for the the input Sherpa parameter par.
Consistent with previous reports [ 39, 40], run convergence was only achieved by setting a uniform prior for branch lengths (prset brlenspr = clock:uniform).
The hierarchy is acquired by setting a Gaussian prior for the marker effects β j | σ j 2 ∼ N (0, σ j 2 ) and an exponential prior to the effect variances σ j 2 | λ ∼ Exp (λ 2 / 2 ).
We set a uniform prior for the hyperparameters, marginalized out condition means and precision, and used an MCMC algorithm to sample α G, β G.
We used the age range of the fossil of Vegavis, an extinct bird related to ducks and geese, to set a uniform prior for the root of our phylogenetic tree, that is, between 66 and 86.5 Ma (Benton and Donoghue 2007).
We were able to set an informative prior for k3 on the basis of published Vmax values for benzene, toluene, ethylbenzene, and m-xylene.
A prior for theta was set at 0.04, based on the mean estimates of theta for the dataset calculated in DnaSP and MEGA 4.1.
By default, Tangram sets a flat prior probability (1/3) for all three possible genotypes.
BEST was implemented by setting the prior for BEST = 1, and unlinking topologies, branch lengths, and mutation rates across loci.
Mr Bayes was allowed to estimate the best fixed rate model of protein evolution during the run by setting the prior for amino acid model to mixed.
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