Sentence examples for setting a phase from inspiring English sources

In the clinical setting, a phase I trial has assessed tolerogenic DCs safety in T1D patients with good results [ 97].

55 In the clinical setting, a phase I/II trial of the MET-TKI crizotinib in combination with erlotinib is ongoing in patients with NSCLC (NCT00965731).

To evaluate the response rate and toxicity of the combination of irinotecan (CPT-11) and cisplatin in a neoadjuvant setting, a phase II study was conducted regarding the regimen of this combination in patients with locally advanced cervical cancer.

Given the favourable toxicity profile of chemoradiation with carboplatin and paclitaxel in the preoperative setting, a phase II study was performed in the Netherlands with concurrent chemoradiation with paclitaxel and carboplatin as definitive treatment for patients with irresectable esophageal cancer.

In the metastatic setting, a phase III trial (CLEOPATRA) of docetaxel and trastuzumab with or without pertuzumab as first-line treatment for 808 patients with HER2-positive MBC showed a significant improvement in progression-free survival and OS with the addition of pertuzumab [ 18, 42].

Although no FRβ-specific mAb has been studied in any clinical setting, a phase 2 trial (NCT00318370) has been completed for a humanized antibody against FRα (Farletuzumab) by Morphotek (Exton, PA, USA) to treat relapsed ovarian cancers after platinum chemotherapy [ 6].

These shifted siRNAs followed the phasing register set by siRNA D8-, indicathat that siRNAs arising from D8- could target and cleave the original transcripts, setting a secondary phasing register different from the register set by miR390.

34 Slow Progress in Trade Talks Trade ministers from around the world made slow progress at a conference in Hong Kong, with setting a deadline to phase out agricultural export subsidies one of the biggest issues to be negotiated.

The paper divides the ISR into four logical phases: setting a computational architectural diagram for each phase, proceeding from functional perspectives (input, process, and output), and their consequences.

We distinguished five phases toward successful goal pursuit: a monitoring phase, a motivational phase, a goal setting phase, a phase of active goal pursuit and an evaluation phase (Table 1).

A clinician setting up a phase II trial should consider the likely mechanism of action the drug will have and choose an end-point that provides high power for that scenario.