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Within this domain, a 'parallel β roll' structure was first described, in which successive β strands are wound in a right-handed spiral and Ca2+ ions are bound within the turns between strands by a repeated GGXGXD sequence, thus setting a paradigm for the RTX portions of the whole protein family.
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"With the availability of Glympse for Autos and our integration with MirrorLink, we are helping to set a paradigm of how connected car apps should be: simple, easy to use and driver-aware," said Glympse co-founder and CEO Bryan Trussel today.
Successive Ca2+-dependent and cosecretional acquisition of a functional RTX toxin structure in the course of T1SS-mediated translocation, through RTX domain folding from the C-terminal cap toward the N terminus, sets a paradigm that opens for design of virulence inhibitors of major pathogens.
What's that story and how did it set a paradigm for the rest of the project?
Our study sets a paradigm for profiling studies using FFPE samples in rare tumors.
When Richard Doll and Austin Bradford-Hill undertook this cohort study, they probably did not realise that they were setting a new paradigm for modern epidemiology, and choosing to do such a study among doctors was quite ingenious.
"This project promises to set a new paradigm for successfully conceiving, financing and delivering transformative infrastructure projects in the United States".
Two recent designs set a new paradigm and option of sleeping in zero-g.
An excellent work published in 2015 by Wang and Chowdhury [100] of UC Berkeley set a new paradigm for memristor and RRAM modeling.
As an inhibitor of the tyrosine kinase activity of the BCR-Abl oncoprotein, imatinib sets a new paradigm for the treatment of cancer with molecularly targeted therapies.
Given the global urban sprawl that runs in favor of the anthropogenic habitats, cities that naturally encompass wildlife will set a future paradigm.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com