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Setting: Multi-institutional university setting.
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The resulting uncertainty can complicate, for instance, data sharing a critical limitation when setting up multi-institutional trials, says Muneesh Tewari, associate professor at the University of Michiganand formerly associate member of the Fred Hutchinson Cancer Research Center (FHCRC), who uses dPCR for microRNA biomarker discovery.
They serve the important functions of generating hypotheses that warrant testing in the setting of multi-institutional or cooperative group trials and by pointing out where these robust datasets fail us, thereby suggesting important data fields that should be incorporated in future registry design.
In this setting, the present multi-institutional TRIP study was designed to determine the efficacy of the combination of EBRT with I-BT boost in all patients treated with uniform widely accepted guidelines for RT in addition to use of HT.
The primary endpoint is to test the safety of SBRT for the treatment of 2 to 4 multiple lesions in several anatomic sites in a multi-institutional setting.
The Cancer and Leukemia Group B designed a phase II trial to test a standardized method of this technique in a multi-institutional setting.
We report the results of a phase II study to determine the reproducibility of a submandibular salivary gland transfer (SGT) surgical technique for prevention of radiation (XRT -induced XRT -inducedn a multi-institutional setting and to assess severity of xerostomia.
The current phase II studies were conducted to further evaluate imatinib in addition to HU in a multi-institutional setting.
The latter is greatly preferred when patients are physically dispersed, and becomes essential in a multi-institutional setting.
Additionally, we will use the first regression schema to be prospectively validated in a multi-institutional setting for the assessment of response.
The ALLIANCE/Intergroup A021101 study is examining the feasibility of mFFX for four cycles followed by RT with oral capecitabine in a multi-institutional setting.
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