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Effective dose was calculated using the two sets of tissue weighting factors given in ICRP Publications 60 and 103.
For orally administered 99mTc-pertechnetate, an effective dose coefficient of 0.016 mSv/MBq was calculated using the sets of tissue weighting factors given in ICRP Publication 60 [15].
IDAC-Dose2.1 calculates absorbed doses to all 47 target regions defined in ICRP Publication 133 [21] and two different sets of tissue weighting factors [15, 19] to estimate the effective dose.
The two sets of tissue sections (dosed animal and spotted control) were then coated with matrix as described above using the Image Prep and subsequently analyzed by imaging mass spectrometry in MS and MS/MS mode, respectively.
Standard sets of tissue samples were collected and cultured as previously described (10 ).
Two sets of tissue specimens were evaluated in the present study.
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Two sets of tissues were prepared, whole hemispheres (ischemic and non-ischemic) and infract core and penumbra regions at 6 and 24 h.
We could have failed to detect some infected animals by missing actively infected tissues, especially since, for some animals, incomplete sets of tissues were available for testing.
Duplication of such genes can facilitate the specialization of daughter genes and changes in expression, for instance in more restricted sets of tissues, can further drive specialization [23].
> -wrap-foot> We now turn to searching for TFs involved in the regulation of sets of tissue-specific genes.
A subsequent k-means clustering (k = 12) revealed sets of tissue-specific co-transcriptionally regulated genes ([ 13] and Figure 3).
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