Sentence examples for sets of somatic from inspiring English sources

These germline mutations can also play a role in forming different subtypes of colorectal cancer, as they trigger accumulation of different sets of somatic mutations throughout carcinogenesis [ 22].

Recent studies have presented genome-wide sets of somatic mutations as a 96-element vector, a procedure that only captures the immediate neighbors of the mutated nucleotide.

First, we show that tumor subpopulations can be spatially segregated in the tumor and carry distinct sets of somatic mutations that reside in different geographical regions.

To identify SMGs and SMPs, we applied the MutSigCV [ 35] and DrGaP [ 36] algorithms to the sets of somatic mutations identified by muTect and VarScan2 and separately to the same sets integrated with the RRA mutations identified by RAREVATOR.

PyClone uses a Bayesian clustering algorithm to group sets of somatic mutations belonging to the same cluster of subclonal cell accounting for allelic imbalances introduced by copy-number alterations and normal-cell impurity.

Many cancers have characteristic sets of somatic mutations that can be used to identify and classify the tumours [ 6]; few studies have even compared these across cancer types [ 7].

A set of somatic cell-derived transcripts upregulated in testes of HDAC inhibitor-treated mice [14] were not significantly changed in Ing2−/− testes (Table S2).

Chemotherapy treatment could cause its own set of somatic mutations [ 24].

The set of somatic mutations in a cancer genome is the aggregate outcome of one or more mutational processes.

117, 118 A heterogeneous set of somatic alterations, including gene amplification, deletion, mutations, and rearrangements, were reported to be involved in the etiology of breast cancer.

A heterogeneous set of somatic alterations, including mutations and gene amplification, are reported to be involved in the etiology of breast cancer.