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These results did not link sets of functionally related sequences (e.g. shared KEGG pathway or COG functional category, not shown).
We therefore need to identify proteins at the intersection of sets of functionally related proteins.
These risk variants aggregate in several sets of functionally related genes, thereby providing novel insights into disease pathogenesis and opportunities for research into discovering new treatments.
This new structure for quartic curves is also exploited to develop various new sets of functionally independent geometric invariants that can be used for object recognition, analogous to feedback invariants used in control system analysis and design.
Comparison of Pum1-associated mRNAs to mRNA targets of PUF proteins from Saccharomyces cerevisiae and Drosophila melanogaster demonstrates how a well-conserved RNA-binding domain and cognate binding sequence have been evolutionarily rewired to regulate the collective expression of different sets of functionally related genes.
GSEA is oriented to identify sets of functionally related genes and is currently used in the analysis of microarray data.
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Our method used sets of functionally- and evolutionarily-related genes to determine if each set has an expression pattern significantly associated with stemness.
Namely, are sets of functionally-related genes differentially- targeted?
In the approach used here a GSA test [ 14] is conducted to relate pre-defined sets of functionally-related genes to a variable that represents the propensity of a gene to be involved in a deletion or in an amplification.
We previously observed that some sets of functionally-related genes are weakly differentially-expressed; here we wish to address a similar, but distinctly different question within the network context.
Put yet another way, the rules are functions of state variables associated with a set of functionally relevant degrees of freedom, which can be implemented differently in different physical media.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com