Your English writing platform
Discover LudwigExact(1)
For all data sets except CFS, which includes family data sets, association of SNPs with SBP and DBP was tested by linear regression with additive genetic model using PLINK; for CFS, association was tested using a linear mixed-effect model that accounted for family structure (32).
Similar(59)
We report sound results of gene sets associations that remained undetected by the conventional one-dimensional gene set analysis in several examples.
In our data set, association between viruses depended on each particular virus-host system.
Therefore, rather than relying on asymptotic distributions of the gene-set association statistics for the KS, FM, SM, TS, MTS and GMRE methods, we use permutations to obtain gene-set association p-values for these methods.
Exploration of core sets of gene interactions is a useful step towards further understanding biological mechanisms underlying the gene-set association with the phenotype of interest.
The gene set association analysis is then based on a likelihood ratio test for the effect of all the PCs included in the model.
Empirical gene-set association P-values were based on 1000 permutations of the phenotype.
We have presented two strategies for increasing power in gene-set association studies.
SKAT is a powerful SNP set association test, which requires very few assumptions [ 31].
As in the Immunochip analysis, in the replication set association was much stronger in the ACA-positive group (P = 3.0 × 10−4), and overall (P = 8.71 × 10−13).
We found some chemicals with similar biological activity profiles in PubChem had similar patterns of chemical-gene set association across the cancer datasets.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com