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Other companies with setbacks include Genentech, which was told to do more study on drugs for psoriasis and asthma.
Setbacks include an alleged bout with cancer, a row with the powerful Muslim Gulenist group, escalating Kurdish violence and the war in Syria.
Those setbacks include deepening frictions within his governing coalition, the recent collapse of the Italian dairy giant Parmalat, wildcat strikes by transportation workers and heated debates over proposed pension revisions.
Those setbacks include increased economic isolation from a range of United Nations sanctions, the mysterious bombing attacks on two Iranian nuclear scientists in Tehran last week and an acknowledgment by President Mahmoud Ahmadinejad that some of Iran's centrifuges, used to purify uranium, had been successfully singled out by Internet saboteurs using malignant software.
Setbacks include the departure of original director Guillermo del Toro in 2010 after extended delays relating to studio MGM's financial travails, a fire that destroyed a number of vital miniatures, an enormous row with a local New Zealand union which prompted the labour law changes, and Jackson's own hospitalisation last year for surgery to treat a stomach ulcer.
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The company went with it, suffering various further setbacks, including bankruptcy.
Other setbacks included 1995's remake of Sabrina and 1999's Random Hearts.
Setbacks included Trump University, Trump Mortgage, Trump Airlines and Trump Vodka as well as four casinos in Atlantic City, New Jersey.
But Acela was not without setbacks, including problems with the undercarriage and electric system,.
More recently, setbacks included an oxygen canister fire and a collision with a fuel resupply vehicle.
This extraordinary discovery emerged after many setbacks, including funding-agency rejections so demoralizing that he considered changing careers.
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