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It was a setback for which he never quite forgave himself.
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The news is a setback for Merck, which has had trouble with Vytorin, which combines Zetia with a different statin.
Nevertheless the likely departure of Mr. Monti is a setback for Europe, which will lose a heavyweight leader, and for Italy, which has experienced a year of unaccustomed influence inside the bloc.
The decision to scrap the $39 billion takeover - which would have been the biggest deal of the year - is a major setback for AT&T, which had pinned its hopes for growth on the acquisition.
It was a major setback for Avalon, which had been lobbying for a significant expansion.
It is also a setback for Sprint which had hoped to piggyback on LightSquared's network.
Boeing's decision was a major setback for Wichita, which has long been an aviation center.
The retreat is a startling setback for Beijing, which rarely yields to popular demand.
The announcement was another setback for Toyota, which until last year appeared all but unstoppable.
Analysts said the move was a setback for MusicNet, which is currently distributed by America Online.
It was a controversial move and a setback for Boeing, which had won the country's two previous jet contracts.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com