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Research involving human subjects done by educational institutions that receive government funding generally must go through an Institutional Review Board, or IRB, that approves the set up of the study before research commences to comply with federal regulations.
The set up of the study included formaldehyde exposures with and without peaks, the presence and absence of a masking agent, and evaluation of the influence of personality factors.
MJV contributed to the set up of the study and helped to draft the manuscript.
This is inherent to the set up of the study and how it was perceived, but it also indicates the connections between clinic, laboratory and research.
In addition, the large scale set up of the study, the high response rates and the great variance in environmental characteristics of the schools and neighbourhoods included in the study all contribute to the quality of the data.
We would like to thank former OCTO staff who were involved with set up of the study; the NCRI Colorectal CSG surgical subgroup for their support and Sue Bulley for the advice on practical aspects of the protocol and trial management.
In the preclinical field, preliminary estimation of the number of experimental units to be included in a study is an important step in the setting up of the study.
LCBAS helped in the design and setting up of the study, contributing to the collection of data.
AH contributed to the setting up of the study sites, participated in its design and coordination and helped to draft the manuscript.
They believe this will remove a lot of repetition at a local level and instead will give trusts more time to work on setting up of the study.
Representatives of the first two funders above participated in discussions during the setting up of the study but none of the funders were involved in study execution nor manuscript preparation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com