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However, for very fast calculation of these many different equilibrium cycle perturbations it is also possible to set up a generalized variational approach.
In addition, once a clustering of SNPs is obtained, we design an individualized genetic score quantifying the SNP composition in each cluster for every subject, so that we can set up a generalized linear model for association analysis able to incorporate the information from a large-scale SNP dataset, and yet with a much smaller number of explanatory variables.
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Finally it is shown that the Chapetti approach was well appropriate to set-up a generalized, local microstructure-dependent fatigue assessment, especially for the investigated AlSi7Cu0.5Mg cylinder head samples.
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