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First, the Wyss scientists set out to probe the degradation of DNA origami in the presence of low salt buffers as well as DNA nucleases and found, as they expected, that their integrity was severely compromised.
The Juno mission set out to probe the hidden properties of Jupiter, such as its gravitational field, the depth of its atmospheric jets and its composition beneath the clouds.
Next, we set out to probe whether the inactivity of FnCas9 on certain endogenous targets was caused by target site and flanking DNA sequence per se by conducting cell-free cleavage assays on a CAR target, which FnCas9 had previously failed to cleave endogenously, using cell lysate from transfected K562 cells as sources of Cas9 proteins.
With his postdoctoral fellow Juliane Bremer and their colleagues, he set out to probe this further.
To establish the evolutionary relationship, geneticist Sean Carroll and his collaborators at the University of Wisconsin, Madison, and Washington University in St . Louisset out to probe the masterminding genes in action.
A team led by Marc Alizon at the Institut Cochin in Paris, in collaboration with Michel Seman at the University of Paris, set out to probe whether HIV may use a CMV protein called US28 to enter some types of cells.
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Convinced that other people "do not feel like they were raised by wolves", Sheila sets out to probe the "ugliness" she feels inside.
With the Citadel, the Roman Catholic Church and "palm-haunted" Charleston as Conroy's familiar backdrops, "South of Broad" — named for the locale of historic houses and blueblood sensibilities near the Battery — sets out to probe the lives of Stephen and Leo's family and friends.
To facilitate biologically significant data interpretation, we set out to enhance probe annotation of the newest Infinium array, the HumanMethylation450 BeadChip (450 k), with >485,000 probes covering 99% of Reference Sequence (RefSeq) genes (National Center for Biotechnology Information (NCBI), Bethesda, MD, USA).
For this purpose, we set out to develop a fluorescent probe for Ca2+ that would operate in a different color region (red) from that of probes for other molecules, many of which show green fluorescence, as exemplified by green fluorescent protein (GFP).
We therefore set out to test our optimized substrate probes using the da Vinci system employing the same workflows that are used in the clinic.
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