In order to see how useful the framework was in uncovering the theoretical rationale, it was applied to a set of trials of acupuncture for fatigue and vasomotor symptoms, identified from a wider literature review of acupuncture and early stage breast cancer.
We reviewed the selected sets of trials for a duplicate check on the sponsor, IMP and indication to avoid miscounting the total number of trials potentially being included in the New Drug Approval list.
It should be noted that, in addition to the scenarios simulated in this study, bias in original trials may also be magnified if the two sets of trials for the AITC are biased in opposite directions.
Another strong point is that the first cohort is based on clinicians recruiting for a set of trials from the nationwide consortium in Obstetrics and Gynaecology.
Even when correlation coefficients were computed on the set of trials (accounting for the inter-individual variability), the index I task) presented the highest correlation coefficient.
For example, the time-frequency decoding of emotion shown in Figure 2 (top panel), used 36360 independent classifiers (36 time points×101 frequencies; at each time-frequency point, 10 classifiers were trained with a different set of 70% of trials for training).
Ultimately, it appears, New York officials could not tolerate ceding much of the city to a set of trials that could last for years.
Network meta-analysis makes similar assumptions to standard meta-analysis of direct comparisons within trials but requires that these assumptions hold over the entire set of trials in the network that is, for the indirect comparisons also.
