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By using a combination of 2D gels, western blots and proteomics, we identified a set of proteins that were recognized by sera from both acute and convalescent patients suffering from meningococcal septicaemia.
Specifically, she was looking at a set of proteins that acted as an alternative to ubiquitin.
A set of proteins that bind the growing plus ends of microtubules.
CRISPR, originally discovered by biologists studying the bacterial immune system, involves a set of proteins that bacteria use to defend themselves against bacteriophages (viruses that infect bacteria).
Functional analysis implicated a set of proteins that localize to a ring-shaped domain between kinetochores during pre-anaphase spindle assembly and anaphase separation.
The scientists used a chemical identification technique known as mass spectrometry to narrow down the set of proteins that had active lysines and cysteines to just those that were metabolic enzymes.
Out of the original set of proteins that could rescue gene deletions, this is the only one that has turned out to be an enzyme — at least so far, she said.
Hence, each HG defines a set of proteins that have distinctly diverged from others; it may contain one ortholog (gene family) or multiple paralogs (gene classes or superfamilies), regardless of their mechanism of origin and traditional classification.
In this study, we quantified a set of proteins that carry out their function in the extracellular fluid, and which are used in the clinic for diagnosing non-communicable diseases (e.g., metabolic syndrome)29.
For instance, is there a critical death substrate or what is the minimal set of proteins that must be cleaved in order to induce the phenotypic hallmarks of apoptosis?
While centromere size is determined by the cellular milieu, centromere positions are heritable and defined by the interactions of a small set of proteins that bind to both DNA and CENH3.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com