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This leads to a set of possible configurations and reconfigurations with a dependency relation between them.
Moreover, it instantiates the MAPE-K architecture and uses a reasoner to search the set of possible configurations for the optimal solution in the current context.
Realistic CR frameworks need to take into account a large set of possible configurations, however, as mentioned hereabove through the Gödel-paradox, the decision making engine also needs to be constrained in order to avoid the system to crash.
Assuming a fixed set of possible configurations, we use a recently-introduced synchronization operator to achieve separation of concerns between adaptation policy, fault tolerance and steady-state system execution.
This generated a set of possible configurations for a predicted series of p53DBD p28 complexes that were ranked based on scoring.
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Because the space of possible configurations isquite large, we applied a selection procedure to pick the most "distinctive"value set.
Four types of possible configurations are identified.
While this does not always tell a user which configuration should be used for a particular application, it serves to reduce the large number of possible configurations by showing which of those are usually "inferior"; a user only has to consider a configuration from the (potentially) much smaller Pareto set rather than every possible combination.
As the number of datasets increases, the number of possible configurations increases exponentially.
A number of possible configurations (bipartite or tripartite) can be envisaged.
The key idea is to consider a discretized version of the set of all possible configurations and use a computationally efficient search technique to find the minimum energy configuration.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com