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In the first pass we augment the set of overlaps by looking for transitive read overlaps.
A path is progressively evaluated in terms of an optimality criteria, encoded by a set of score functions based on the set of overlaps along the lay-out.
With a set of overlaps chosen according to these criteria (the trypsinogen second set of modules), 97% of constructs obtained contained only correctly ligated DNA ends.
The subsequent step of scaffolding the unitigs and then expanding the set of overlaps allows Phrap to indirectly use mate pair information in building its final contigs.
In the second pass through the reads we use the augmented set of overlaps to better identify false overlaps using the correlation test.
If this is the case, we then create an extended set of overlaps consisting of the reliable overlaps combined with plausible overlaps of the end reads from the adjacent contigs.
Similar(42)
Herein, a segment of the spectrogram is defined as a set of overlapping short-time windows and the entire frame is represented as a set of overlapping segments.
The National Park Service, the Sierra Club, the National Trust for Historic Preservation have all questioned the museum's scale, location and style — a sleek set of overlapping white boxes — amid Victorian brick buildings with wooden porches and pitched roofs.
Set of overlapping primers used for amplification of HKT genes.
The device consists of two in-plane 180° out-of-phase vibrating masses with a set of overlapping light-reflecting beams behaving essentially as a lamellar grating.
Using another vaccine design tool called the EpiAssembler, a new set of overlapping, conserved and immunogenic HIV-1 peptides were engineered creating extended "immunogenic consensus" sequences.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com