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The new microplate screen identified a broader set of mutations than the previously employed X-gal colony screen.
One set of mutations is represented by deletions that begin at the HpaII site and extend unidirectionally for varying lengths toward the BglI site at ori.
This set of mutations matched FIPV's behavioral change and appeared across samples with consistency unparalleled in the quest for the mutation.
But within the two broad groups of cancer, any particular tumour had its own set of mutations.
It will be the first comprehensive center to focus on a specific set of mutations known to cause cancer.
Each version had its own set of mutations that it acquired after the virus had invaded our ancestors.
The H5 virus has been present in the human population since the late 1950's, said Dr. Offit of Children's Hospital, but has never acquired the full set of mutations needed to set off a pandemic.
Recently, Timothy Ley, a researcher at Washington University, in St . Louis and an expert on the genetics of blood cancers, published a study involving two hundred patients with A.M.L.; he found that each patient harbored a unique set of mutations.
For the first time, researchers have decoded all the genes of a person with cancer and found a set of mutations that may have caused the disease or aided its progression.
Pinpointing a small set of mutations within the binding pocket greatly improves the difference in binding energies between targeted and decoy ligands, even when they are very similar.
We end by proposing a set of mutations altering the swapping propensities, whose experimental characterization would contribute to refine our in silico derived hypotheses.
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CEO of Professional Science Editing for Scientists @ prosciediting.com