Suggestions(2)
Exact(6)
Further close investigation and comparisons are made by selecting a set of hotspots.
Criteria in selecting a set of hotspots may vary across studies, as there is no any universal rule of selection.
Given a set of hotspots with the local ideal correlator radius for the hotspot referred to as, the global ideal correlator radius is set as where.
We also used the top 5% recombination rate scores to select a second set of hotspots.
A second set of hotspots, likewise, were defined on the basis of the top 5% recombination rates.
This allows quick manual construction of a set of hotspots, and also provides a way to use our visualization approach for hotspots detected by other Cytoscape plugins.
Similar(54)
At the local level, females and males tend to use similar sets of hotspots, but nearly half of all intervals exhibiting any activity were active in only one sex.
An open question is how local and distal factors shaping recombination rates, such as trans-acting DNA-binding proteins, chromatin structure, and interference, combine their effects to achieve similar regional recombination rates along the chromosomes when using different sets of hotspots.
Finally, the motifs determine hotspot activation at the initiation of recombination events [12]; since interference imposes significant constraints on crossover positioning, the set of crossover hotspots could be only a fraction of the initiating hotspots, or show different frequency distribution along the chromosomes.
This analysis was repeated using the same set of 500 hotspots, following application of the appropriate SUVref filter to each reconstruction prior to measurement of the maximum voxel intensity, to compute percentage change in SUVref (Δ SUVref).
To rule out this possibility, we used a set of 9290 hotspots and corresponding coldspots that were matched for length and SNP density [40].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com