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A large set of expression data including expressed sequence tags (ESTs) and transcriptional profiles of this important fungal pathogen are now available.
The HubDetector algorithm ranks the genes according to the number of times they are differentially expressed across a set of expression profiles.
This is due to the insufficient set of gallery images that could span the entire set of expression changes.
We have engineered and validated a set of expression platforms that regulate transcription through a secondary structural switch that can host a variety of different aptamers, including those derived through in vitro selection methods, to create novel chimeric riboswitches.
Principal Component Analysis (PCA) is a decomposition technique that produces a set of expression patterns, or principal components.
EBarrays is an empirical Bayes approach which models the probability distribution of a set of expression measurements [79], [80].
Each gene in the genome becomes associated with a set of expression values, called gene expression profile.
In particular, a set of expression profile data, calcium level data, and cAMP level data for single ligand assay in both B-cells and macrophages was used.
The complete set of expression data is presented in Fig. S1A and have been deposited in the Gene Expression Omnibus (GEO; http://www.ncbi.nlm.nih.gov/geo) under accession GSE15888.
Given a training set of expression vectors (of values across metagenes) representing two biological states, a binary probit regression model is estimated using Bayesian methods.
Using expression data from the literature and derived from our own research program we developed a limited set of expression markers that would likely be altered in association with prostate cancer progression.
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