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The usefulness of indicators related to this first subsystem for assessing nursing care performance may be justified on several grounds: The indicators mentioned above may reveal a broad set of dysfunctions and deficiencies, such as insufficient supply of basic material resources, gaps between nurse staffing and patients' needs, heavy workload and staff instability.
There is another underestimated variable which needs to be taken into account and using cancer as an example may reveal further problems: Cancer is not one disease and contains a heterogeneous set of dysfunctions such that the information available for biomarkers are also heterogeneous.
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15 This supports the hypothesis that the same set of biological dysfunctions can contribute to susceptibility to a range of clinical phenotypes including prototypical schizophrenia and prototypical bipolar disorder.
A lot of dysfunction starts there".
Hence a more plausible explanation is that the abnormality in semantic categories and the related "loosening of associations" is part of the set of common base dysfunctions, which "surfaces" in various symptoms.
Telomerase reactivation in the setting of telomere dysfunction enabled full malignant progression with alleviation of telomere dysfunction-induced checkpoints.
Vasopressin levels are often elevated in patients with heart failure and left ventricular (LV) dysfunction, 20 and they are clearly associated with adverse cardiovascular outcomes in the setting of LV dysfunction after myocardial infarction.
Myocardial relaxation and diastolic function will be abnormal in the setting of systolic dysfunction.
Ultrafiltration is an alternative to loop diuretics but has not proved advantageous in the setting of renal dysfunction, and if not carefully applied may also aggravate neurohormonal imbalance.
Vascular reconstruction along with major liver resection in the setting of liver dysfunction caused by biliary obstruction can be associated with increased risk.
In contrast, telomerase reactivation in the setting of telomere dysfunction alleviated intratumoral DNA-damage signaling and generated aggressive cancers with rearranged genomes and new tumor biological properties (bone metastases).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com