Each watch is built in 18-karat yellow gold to underscore the brilliance of the yellow diamonds, and each features diamonds in round and fancy ovals that are meticulously set by hand, as well as finished and polished by hand.
Since the model was designed to describe experiments where spiking is induced artificially by the experimenter, firing is not an intrinsic property of the model but firing times were set 'by hand' at the target times designated for current injection by the experimental protocol.
But smaller jobs are set by hand, using techniques Gutenberg himself would recognise.
Mr. Happel first created a prototype of the pattern with each crystal set by hand.
If books were still set by hand, would the printer of "War Dances" have run out of question marks?
He had painstakingly tested his data set by hand and found evidence that the computer might be discovering hormonal signals in facial structure.
For all their sophisticated tools, many designers get ideas from graphic artists who worked before computers, when all type was laboriously set by hand rather than formulated digitally.
Those with machine-set bristles are $3.50, but those with bristles set by hand, much more tightly packed, bound with stainless steel wire and backed with an extra slab of wood to conceal the wire, are priced from $13.50.
During the last century, when type was set by hand, printers applying for a job would set up an Ulster County Gazette of Jan . 4 ,800, as a test of skill.
This suggests that two traits are needed to endure in a job that has changed, in Mr. Bruno's time, from the Ben Franklin-era technology of lead type set by hand to today's laser printers.
