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In our data set, association between viruses depended on each particular virus-host system.
The gene set association analysis is then based on a likelihood ratio test for the effect of all the PCs included in the model.
Results for data generated under the null hypothesis of no gene set association were used to assess type 1 error rate, while results for data generated under the alternative hypothesis were used to assess power.
We found some chemicals with similar biological activity profiles in PubChem had similar patterns of chemical-gene set association across the cancer datasets.
We applied the same rotation procedures for each dataset respectively as described above, and tested the latent factors for gene set association by GSA (Additional file 1, Figures S9 ~ S12).
This gene set association corroborates previously identified links between PD and inflammation (Knott et al., 2000) and reports of elevated levels of interleukin-6 in the cerebrospinal fluid of PD patients (Blum-Degena et al., 1995).
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Regarding the effects of PM mass on cardiovascular mortality, in the limited species data set, associations were observed for lag 1 PM2.5 and PM10.
Photo grouping is designed for setting associations between groups of photos.
By using the temporally maintained identification set, the association system has a group association condition by (14).
The recognition of tissue-specific gene/protein set associations is often statistically infeasible.
We refer to significant chemical-gene set associations to gene expression data as "associations" or "predictions" in the following.
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