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Set Small Targets.
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Build motivation by setting small targets, then making them big.
Set small goals.
Set small and achievable goals.
Set small and measurable goals.
Set small goals for yourself.
We have to set ourselves small targets and get to those.
Given our small target set and the rare nature of indels, it is difficult to provide a precise measurement of our accuracy for indels, although our data do suggest that the use of GATA substantially improves our ability to detect small lesions.
Finding a simple combination of enzymes to manipulate for improving a desirable trait is formally equivalent to finding a (small) set of drug targets, and is certainly a combinatorial optimisation problem, and it does seem to be the case that a small number of carefully chosen targets can often have large effects (e.g. 14, 59– 61).
When mouse and human mature microRNAs were plotted graphically (data not shown), we observed large hubs representing microRNAs with large target sets of mainly GC-rich mature microRNAs, which agglomerated satellites of microRNAs with small target sets.
This second definition completely ignores differences between the number of targets; therefore, microRNAs with small target sets are easily scored as very similar to microRNAs with large target sets.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com