However, the highest gain along all sessions is achieved when both players always cooperate (resulting in 4 food pellets every trial).
Patients who reach the primary outcome of catheter malfunction will also be followed for an additional one month period, or until either: 1) six consecutive successful hemodialysis sessions are achieved (defined as a mean blood flow of ≥ 300 ml/min at each run in the two week period), or 2) the catheter is removed.
In the subsequent voting session, consensus was achieved on the following points (Table S1 for detailed voting results): The core outcome measure for the clinical signs domain should include erythema, excoriation, oedema/papulation and lichenification as a minimum to achieve content validity.
In the post-test, after the 6 practice sessions, mastery was achieved at all levels except the most difficult.
During the three iterative web-based blinded evaluation sessions, consensus was achieved on 63/106 cases (59.4%), with 13 patients declared as inactive, 49 as active (26 with low activity, 13 with moderate activity, 10 with high activity), and one patient was not evaluable (wrong diagnosis) by consensus.
Patients in this study were scheduled for three embolization sessions unless CR was achieved with fewer sessions; after these scheduled sessions, they were treated with embolization only on demand.
Regular adherence, defined as at least one training session per week, was achieved by around 85% in both groups in the supervised training periods.
Standard administration and scoring of the Wechsler Abbreviated Scale of Intelligence test was demonstrated by, and practised under the supervision of local child psychologists and psychiatrists with experience in IQ testing in children; during the training session, high interpaediatrician agreement was achieved on repeat testing of the same children.
At the end of the recording session, extracellular iontophoresis of Neurobiotin was achieved with positive current pulses (200 ms on/200 ms off; +600 nA during 5 min) delivered by a microiontophoresis current generator (SYS-260; WPI, Sarasota, FL, USA).
All rats received a minimum of three PR sessions (15 20 total training sessions) during which stable cocaine intake was achieved.
