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The UBL domain interacts with the proteasome and also with proteins containing ubiquitin-interacting motifs (UIMs), while the UBA domain serves to interact with polyubiquitinated proteins, at the same time protecting ubiquilins from proteasomal degradation [ 14- 20].
The SOCS box, placed at the C-terminus serves to interact with Elongins C and B, cullin5 and Rbx2 forming the catalytic core of the complex [39], [40].
The SH2 domain of SOCS2 serves to interact with phosphotyrosine residues the targeted substrate directing the specificity of the ubiquitin ligase reaction [39].
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The highly divergent N-termini of CENP-A is localized outside the nucleosome and should serve to interact with other kinetochore proteins including histones [ 4, 13].
This has important implications for psychological conceptions of word meaning, as it shows that word meaning is grounded in systems that serve to interact with the external world, rather than in purely symbolic or abstract codes.
Although the sequence similarity between microbial and animal rhodopsins is low, they share in TM7 a specific Lys residue for retinal attachment, and in TM6 they share homology for two aromatic residues that serve to interact with the retinal (Trp265 and Tyr268 in bovine Rho).
If a user has a question, this same IM window serves as your way to interact with them.
For those who have not had the opportunity to try Brizzly yet, it's a web app that serves as a way to interact with both Twitter and now Facebook.
Carambola, which was founded back in 2011 and raised a $1 million seed this July, has built a platform to automate the process of making online video content interactive — by scanning the video and using proprietary algorithms to determine contextually relevant additional content to serve up for users to interact with.
Each monomer of L12 NTD is formed by two antiparallel helices and serves as a dimerization module to interact with the NTD of another L12 monomer.
The Snail/Gfi-1 (SNAG) domain of Snail/Slug assembles a histone H3-like structure and serves as a molecular 'hook' to interact with the LSD1 CoREST complex, and brings this complex to its targeted gene promoters through the binding of the E-box through the zinc-finger motifs (Lin et al, 2010; Ferrari-Amorotti et al, 2013).
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