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The siRNA is then incorporated into one or more of the Argonaute proteins in RISC where the RNA serves as a sequence specific guide for complementary base pairing with the target and guides RISC for sequence specific target degradation or translational inhibition (Hammond et al, 2000; Tuschl et al, 1999).
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The motif is generally designated GARP (GOLDEN2, ARR, PSR1), which serves as a sequence-specific DNA-binding domain.
In either case, they would not simply represent transcriptional noise, but could serve as a sequence pool for the development of novel functional genes.
BBGD was established in 2005 to serve as a sequence and microarray database for the blueberry community with its primary focus to store and analyze ESTs and microarray data generated from experiments aimed at studying cold acclimation and mid-winter hardiness of blueberry.
By convention one particular sequence, known as the revised Cambridge Reference Sequence (rCRS), or the Anderson sequence, serves as a reference sequence [1], [2].
By contrast, serving as a sequence-unrelated control, scrambled siRNA did not exert any detectable effect.
The subfamily II receptors contain a fourth transmembrane domain, which possibly serves as a signal sequence for membrane targeting.
The TMD of transferrin receptor serves as a signal sequence for recognition by SRP as previously described (Mariappan et al., 2010).
The [4Fe 4S] cluster is ligated by three Cys residues that reside typically in a CX3CX2C motif, which serves as a signature sequence for RS enzymes.
The chi sequence on DNA triggers switching of RecBCD enzyme from DNA degradation to recombination repair and thus serves as an ID sequence of a genome.
This localization is a result of Spire1C's unique ExonC domain, which serves as a mitochondria-targeting sequence.
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