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It is believed that this domain arrangement initially served to target kinases to their substrates [ 4].
Staff also feels encouraged by knowing that their performance is monitored and that this served to target support responding to their actual needs.
Nevertheless, we believe the Goa workshop served to target many of the major public health concerns associated with climate change and began the process of conceptualizing research needs and approaches that are integrative and achievable in low- and middle-income countries.
In a setting where decisions are often made by grandmothers and husbands and community leaders rather than individual women, this suggests that public health interventions would be well served to target the broader community, specifically grandmothers, fathers and local healers when trying to increase appropriate breastfeeding rates.
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They serve to target drug molecules in specific regions through size manipulation and surface modification.
This could serve to target the drug to the protozoan surface and increase its efficacy in vivo.
Drugs conjugated to HA could also serve to target the drug to cells or tissues in the body that are rich in HA-binding receptors, such as CD44, RHAMM, TLR2, and TLR4.
In the Lpp-OmpA vector, the Lpp domain serves to target and anchor the tribrid to the OM and the OmpA domain is required for the surface expression of the passenger.
Hence, this strategy serves to target diseases that affect the MPS.
Furthermore, HDAC3 serves to target this specifically phosphorylated TR2 to PML NBs for its subsequent SUMOylation.
Both these proteins recognise primarily polar transmembrane regions, as would be exposed by misfolding of the membrane-spanning portion of a polytopic protein, and they serve to target proteins to the vacuole.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com