BubR1, similar to its orthologue Mad3 in yeast (Burton and Solomon, 2007; Sczaniecka et al, 2008), has a D-box-like motif and two KEN boxes, which serve as destruction signals for the APC/C complex (Glotzer et al, 1991; King et al, 1996b; Pfleger and Kirschner, 2000).
In insects, haemocytes are circulating cells that are responsible for the cellular response by encapsulation and phagocytosis [42] during which ROS production will serve for pathogen destruction [43].
Its indiscriminate application of death and destruction serves as a recruitment vehicle, with scores of new jihadists rising up to replace each individual who might have been killed by a missile attack.
The hope is that this public act of destruction will serve as a turning point.
In principle, tRNA destruction could serve to reduce the cell's translational capacity and thereby reduce protein influx into the ER, akin to protein kinase-like ER kinase (PERK) activation in metazoan cells.
To some of them, its destruction serves as an epitaph of sorts, the end of eras in Iraq and the Arab world and the eclipse, in war and strife, of the ideal he represented.
Although nuclear weapons are never mentioned in the original Battlestar Galactica, nuclear destruction serves as the grist in several more leftish accounts of the end of the cold war, including the Terminator series.
Old Testament-style destruction served with a smile.
For some, the station's destruction served to underscore the failure of United States intelligence to predict the attacks.
But blasted three blocks into town or dumped implausibly onto roofs of seaside retreats, their destruction served notice that for all the romance of the ocean, it can also wreak havoc — and in a warming world, increasingly does.
