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We hypothesized that tumor microRNAs (miRNAs) could serve as predictive biomarkers for chemoresistance and prognostic biomarkers for survival of patients with SCLC treated with systemic chemotherapy.
These markers could be useful as markers for EMT in breast cancers and may serve as predictive markers for designing customized therapy in the future.
Presence of the 4q12 amplicon and subsequent over-expression of PDGFRA might serve as predictive markers for efficacy of sunitinib.
As already noticed, this is a question of non negligible importance, especially when models are built to serve as predictive tools.
SAG is currently in clinical development and has been evaluated in phase II trials in NSCLC [53]; [54] therefore investigations whether mutational status of TP53 could serve as predictive biomarker in clinical trials warrants further investigation.
CRC is a heterogeneous disease and the three polymorphisms used in this study may serve as predictive markers in at-risk individuals for early identification of MSI and selection of optimal therapies.
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Both studies confirmed that BRCA1/2 mutational status serves as predictive markers for PARPi.
Therefore, we conducted this systematic review aiming to provide a comprehensive and up-to-date overview on the biomarkers that can be served as predictive surrogates for clinical outcomes in patients with GC.
Our model predicts the clotting time and anti‐FXa effects and could thus serve as a predictive tool for the anticoagulant potential of a new compound.
Studies have suggested that quality of life (QOL) evaluation before video-assisted thoracoscopic sympathectomy for patients with hyperhidrosis may serve as a predictive factor for positive postoperative outcomes.
Furthermore, the model may serve as a predictive tool to design and test strategies for the cellular use of antisense oligonucleotides.
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