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While some phenolic compounds occur constitutively and serve as pathogen inhibitors in non-host resistance [ 61, 62], others are synthesized de novo in response to fungal infection and act as part of an active defense response [ 63].
Since the cell wall serves as the interface between the pathogen and the host immune defense, components of the cell wall serve as pathogen associated molecular patterns and virulence factors.
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During RNA virus infection, double-stranded RNAs (dsRNA) and uncapped transcripts generated during replication can serve as pathogen-associated molecular patterns recognized by innate immune receptors [1], [2].
Moreover, increased production of the 5'trailer RNA may also serve as a pathogen associated molecular pattern generating a potent live attenuated vector with natural adjuvant properties.
In the context of the new PSD model [ 7], these data suggest that many previously unrecognized bacteria might serve as accessory pathogens that contribute to collectively elevating the virulence of dysbiotic microbial communities, stimulating chronic inflammation and disrupting homeostasis, ultimately leading to periodontal tissue destruction.
11 Lipoarabinomannan (LAM) is a prominent glycolipid in the cell wall of TB and may serve as a useful pathogen biomarker to assess response to anti-TB therapy, particularly among HIV-infected adults.
Many major human diseases are produced by microorganisms conveyed by insects, which serve as vectors of pathogens.
However, one team of researchers published a 2013 report suggesting menus can serve as vehicles for pathogens such as salmonella and E. coli.
Many protists are intimately associated with bacteria or microbial eukaryotes, which serve as food sources, pathogens, or symbionts.
We propose that the epithelium serves as a pathogen "boot camp" that trains MAP for efficient long-term survival within the macrophage phagosome.
Marinades and especially their spices may potentially serve as sources of food pathogens, and furthermore promote pathogen survival.
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