Exact(2)
Consistently with the absence of stx, the chromosomal loci which serve as integration sites for stx-converting bacteriophages in EHEC O157 H7/NM (yehV, wrbA, yecE) [14], [15] and EHEC O26:H11/NM (wrbA, yecE) [16] were unoccupied in each of the stx−/eae+ strains of the respective serotypes.
Transcription factors (TFs) are proteins that regulate gene expression, which serve as integration centers of the different signal-transduction pathways affecting a given gene [ 19].
Similar(58)
Although most currently known genomic islands are located at the 3' end of a tRNA locus, other genes serving as integration sites have been described, such as the glr (glutamate racemase) gene of the Helicobacter pylori pathogenicity island [82].
Further, it can serve as an integration basis for existing information models.
Three types of cooperation at the individual or collective level and that increase in intensity are identified: consultation (movement actors serve as advisors), integration (actors serve on panels and committees to develop public policies) and delegation (actors assume responsibility for certain tasks in policy implementation).
We propose that enhancers serve as information integration hubs, at which instructions encoded by the genome are read in the context of a specific cellular state, signaling milieu and chromatin environment, allowing for exquisitely precise spatiotemporal control of gene expression during embryogenesis.
These insertion sites serve as neutral integration sites for all transgenes of interest containing the attB site.
Besides their benefits in terms of dissemination of organisational knowledge, such communities can also serve as talent integration tools and help to strengthen the sense of belonging to an organisation.
CREB5 has also been noted to serve as an integration site for xenotropic murine leukemia virus-related virus (XMRV) in prostate cancer tissue from patients homozygous for a reduced activity variant of the antiviral enzyme RNase L [ 92].
Integration of retroviral DNA is catalyzed by the viral enzyme integrase (IN), and one salient feature of retroviral DNA integration is its lack of specificity, as many chromosomal sites can serve as targets for integration.
They serve as indicators of integration ages as well as genomic recombination events that occurred in the host after the initial integration.
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