Sentence examples for serum shift from inspiring English sources

To overcome this limitation, targeted serum shift prediction models were generated for each subclass of interest and were applied to the design of prospective analogs.

The new analogs exhibit excellent in vitro antiviral activity against wild-type (wt) virus and a lower serum shift when compared with the prototypical HIV-1 MI bevirimat (1, BVM), the first MI to be evaluated in clinical studies.

These efforts culminated in the synthesis of compound 10, a potent inhibitor with low serum shift that demonstrated greatly improved in vivo efficacy in two distinct rat infection models.

In order to identify candidates suitable for in vivo validation of the target, serum shifted potency and pharmacokinetic properties were determined for several compounds.

Poonawalla also continually tinkers with technology to get higher yields; Serum shifted from making measles vaccines in small flasks to producing them in larger, more cost-efficient quantities in cell factories.

Serum deprivation shifted the pK value for intracellular H+ to alkaline values (alkaline shift) and increased the slope of the relationship.

To measure proliferation, 800 1200 cells/well were plated in 96-well plates and kept overnight in DMEM containing 2% horse serum, before shifting the cells to the same medium supplemented with the specific growth factor (day 0): EGF (100 ng/ml, Sigma), bFGF (10 ng/ml), PDGF-BB (0.4 nM) or HGF (20 ng/ml).

The three-facet diagnostic criteria used by the research team to confirm refeeding syndrome is displayed in table 2. Each participant's medical team diagnosed the refeeding syndrome using serum electrolyte shifts and observed clinical complications of acute circulatory fluid overload and organ dysfunction.

Laboratory values were PaO2 63.4 mm Hg, hemoglobin 11.9 g/dL, thrombocytes 109 × 10/mm, leukocytes 11.05 × 10/mm with a left shift, serum albumin 2.6 g/dL, alanine aminotransferase 108 U/L, and total bilirubin 2.57 mg/dL.

Consistent with this hypothesis, viral variants that emerged in vivo following infection with a clonal preparation of GL8, and which resisted neutralisation by homologous serum, displayed a shift in receptor usage from CRD2-dependent to CRD-2 independent [ 23 ].

In the short term, lactic acidosis is adaptive because a decrease in serum pH would shift the hemoglobin-oxygen dissociation curve rightward and allow for increased delivery of O2 to tissues.